TAK-580
TAK-580 (MLN2480) is an investigational small molecule that potently and selectively inhibits all Raf kinase isoforms. It has been utilized in preclinical research to study oncogenic signaling pathways, demonstrating activity in both in vitro cellular assays and in vivo tumor models relevant to cancer research.
Product Specifications
CAS Number
1096708-71-2
Product Name Alternative
BIIB 024, BIIB024, BIIB-024, Inhibitor, inhibit, MLN 2480, MLN2480, MLN-2480, Raf kinases, Raf, TAK580, TAK-580, TAK 580, Tovorafenib
Field of Research
Epigenetics & Chromatin, Signal Transduction
Purity
98.42% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween-80+45% Saline:1 mg/mL (1.98 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:93 mg/mL (183.69 mM) ; Ethanol:93 mg/mL (183.69 mM)
Smiles
CC (NC (=O) c1ncnc (N) c1Cl) c1ncc (s1) C (=O) Nc1cc (c (Cl) cn1) C (F) (F) F
Molecular Formula
C17H12Cl2F3N7O2S
Molecular Weight
506.29
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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