What is the catalog number for Monomethyl auristatin E?

The catalog number for Monomethyl auristatin E is orb1300366.

What sizes are available for Monomethyl auristatin E?

Monomethyl auristatin E is available in the following size(s): 5 mg, 10 mg, 25 mg, 50 mg, 100 mg.

How many pack sizes does Monomethyl auristatin E come in?

Monomethyl auristatin E is available in 5 different pack sizes.

Is Monomethyl auristatin E in stock?

Monomethyl auristatin E is currently made to order / not held in immediate stock. Contact us for lead time.

Monomethyl auristatin E

Monomethyl auristatin E (MMAE) is a potent tubulin polymerization inhibitor that disrupts cell division. It serves as the cytotoxic payload in numerous antibody-drug conjugates (ADCs) and is widely used in oncology research for both in vitro cytotoxicity studies and in vivo xenograft models.

Product Specifications

CAS Number

474645-27-7

Product Name Alternative

Microtubule Associated, microtubule, MicrotubuleAssociated, Microtubule/Tubulin, MMAE, inhibit, Inhibitor, Monomethyl auristatin E, ADCCytotoxin, ADC Cytotoxin, ADC Payload, Apoptosis, SGD 1010, SGD1010, SGD-1010, Vedotin

Field of Research

Cell Biology, Signal Transduction

Purity

98.47% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (2.79 mM) ; DMSO:71.8 mg/mL (100 mM)

Smiles

CC[C@H] (C) C ([C@@H] (CC (=O) N1CCC[C@H]1C (OC) [C@@H] (C) C (=O) N[C@H] (C) [C@@H] (O) c1ccccc1) OC) N (C) [C@@H] (C (C) C) C (=O) NC (=O) [C@@H] (NC) C (C) C