Motolimod
Motolimod (VTX-378/VTX-2337) is a potent and selective small molecule agonist of Toll-like receptor 8 (TLR8), exhibiting an EC50 of 100 nM and over 50-fold selectivity against TLR7. It is utilized in immunological research to study innate immune activation and has been investigated in preclinical models for its potential in cancer immunotherapy and as a vaccine adjuvant.
Product Specifications
CAS Number
926927-61-9
Product Name Alternative
VTX-2337
Field of Research
Cell Biology, Immunology & Inflammation
Purity
>98%
Bioactivity
TLR8 Agonist
Form
Powder
Solubility
Soluble in DMSO (up to at least 25 mg/ml)
Smiles
CCCN (CCC) C (=O) C1=Cc2ccc (cc2N=C (N) C1) -c1ccc (cc1) C (=O) N1CCCC1
Molecular Formula
C28H34N4O2
Molecular Weight
458.61
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
2-Amino-N, N-dipropyl-8-[4- (pyrrolidine-1-carbonyl) phenyl]-3H-1-benzapine-4-carboxamide
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
