MRT68921
MRT68921 is a potent dual inhibitor of the autophagy-initiating kinases ULK1 and ULK2, exhibiting IC50 values of 2.9 nM and 1.1 nM, respectively. This compound is a valuable research tool for investigating autophagy mechanisms and has been utilized in both cellular and in vivo studies to probe autophagy-dependent processes in cancer and other diseases.
Product Specifications
CAS Number
1190379-70-4
Product Name Alternative
MRT 68921, MRT-68921, MRT68921, ULK, ULK1, ULK2, Unc-51 like kinase
Field of Research
Cell Biology
Purity
98.00% (May vary between batches)
Solubility
H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:10 mg/mL (23.01 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.3 mM)
Smiles
N (CCCNC (=O) C1CCC1) C=2C (=CN=C (NC=3C=C4C (=CC3) CN (C) CC4) N2) C5CC5
Molecular Formula
C25H34N6O
Molecular Weight
434.58
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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