NPS-1034
NPS-1034 is a potent small molecule inhibitor targeting both Met and Axl kinases, exhibiting IC50 values of 48 nM and 10.3 nM, respectively. It is a valuable research tool for studying oncogenic signaling in vitro and has shown efficacy in reducing tumor growth in preclinical in vivo cancer models.
Product Specifications
CAS Number
1221713-92-3
Product Name Alternative
CMet, c-Met, cMet/HGFR, c-Met/HGFR, Axl, AXL, Apoptosis, Inhibitor, HGFR, Met, inhibit, NPS1034, NPS-1034, NPS 1034, Mer, Tyro3, TAM Receptor, TAMReceptor
Field of Research
Cell Biology, Neuroscience, Signal Transduction
Purity
97.86% (May vary between batches)
Solubility
H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:93 mg/mL (168.62 mM) ; Ethanol:4 mg/mL (7.25 mM)
Smiles
Cc1c (C (=O) Nc2ccc (Oc3ccnc4[nH]cc (-c5ccccc5) c34) c (F) c2) c (=O) n (-c2ccc (F) cc2) n1C
Molecular Formula
C31H23F2N5O3
Molecular Weight
551.54
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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