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NSC 228155

NSC 228155 is a small molecule activator of the Epidermal Growth Factor Receptor (EGFR) . It functions by binding to the dimerization domain (Domain II) of soluble EGFR, thereby modulating its tyrosine phosphorylation. This compound is utilized in biochemical and cellular research to study EGFR signaling pathways in both in vitro and in vivo experimental models.

Product Specifications

CAS Number

113104-25-9

Product Name Alternative

DNA Synthesis, DNASynthesis, ErbB-1, Epigenetic Reader Domain, EpigeneticReaderDomain, Epidermal growth factor receptor, EGFR, Inhibitor, HER1, HistoneAcetyltransferase, Histone Acetyltransferase, HATs, HAT, inhibit, NSC 228155, NSC228155, NSC-228155, KIX-KID interaction, RNA Synthesis, RNASynthesis

Field of Research

Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Molecular Biology, Neuroscience, Signal Transduction

Purity

96.64% (May vary between batches)

Solubility

Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+90% Corn Oil:1 mg/mL (3.45 mM) ; DMSO:7.34 mg/mL (25.29 mM)

Smiles

[O-][N+] (=O) c1ccc (Sc2cccc[n+]2[O-]) c2nonc12

Molecular Formula

C11H6N4O4S

Molecular Weight

290.25

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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