NSC 228155
NSC 228155 is a small molecule activator of the Epidermal Growth Factor Receptor (EGFR) . It functions by binding to the dimerization domain (Domain II) of soluble EGFR, thereby modulating its tyrosine phosphorylation. This compound is utilized in biochemical and cellular research to study EGFR signaling pathways in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
113104-25-9
Product Name Alternative
DNA Synthesis, DNASynthesis, ErbB-1, Epigenetic Reader Domain, EpigeneticReaderDomain, Epidermal growth factor receptor, EGFR, Inhibitor, HER1, HistoneAcetyltransferase, Histone Acetyltransferase, HATs, HAT, inhibit, NSC 228155, NSC228155, NSC-228155, KIX-KID interaction, RNA Synthesis, RNASynthesis
Field of Research
Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Molecular Biology, Neuroscience, Signal Transduction
Purity
96.64% (May vary between batches)
Solubility
Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+90% Corn Oil:1 mg/mL (3.45 mM) ; DMSO:7.34 mg/mL (25.29 mM)
Smiles
[O-][N+] (=O) c1ccc (Sc2cccc[n+]2[O-]) c2nonc12
Molecular Formula
C11H6N4O4S
Molecular Weight
290.25
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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