Olmutinib
Olmutinib (HM61713) is an orally bioavailable, mutant-selective EGFR inhibitor with antineoplastic activity. Its selectivity for mutant EGFR, including T790M, may reduce toxicity relative to non-selective inhibitors. It has demonstrated efficacy in both in vitro assays and in vivo models of non-small cell lung cancer (NSCLC) .
Product Specifications
CAS Number
1353550-13-6
Product Name Alternative
T8460, 1802181-20-9, BI1482694, BI-1482694, BI 1482694, BTK, HER1, Inhibitor, HM 61713, HM61713, HM-61713, HM61713, BI 1482694, HM61713, BI1482694, HM61713, BI-1482694, EGFR, EGFR (cell: H1975), EGFR (cell: HCC827), Epidermal growth factor receptor, ErbB-1, Olmutinib, inhibit
Field of Research
Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction
Purity
97.46% (May vary between batches)
Solubility
DMSO:90 mg/mL (184.96 mM) ; Ethanol:22 mg/mL (45.21 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (10.28 mM)
Smiles
CN1CCN (CC1) c1ccc (Nc2nc (Oc3cccc (NC (=O) C=C) c3) c3sccc3n2) cc1
Molecular Formula
C26H26N6O2S
Molecular Weight
486.59
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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