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ORY1001

ORY1001 is a potent, orally bioavailable, and selective inhibitor of the epigenetic enzyme LSD1/KDM1A, exhibiting an IC50 of <20 nM with minimal activity against related FAD-dependent oxidases. It is utilized in research to study oncology, hematopoiesis, and neurological disorders, demonstrating activity in both cellular assays and in vivo animal models.

Product Specifications

CAS Number

1431326-61-2

Product Name Alternative

ORY 1001, ORY1001, ORY-1001, ORY-1001 (RG-6016), LSD1/KDM1A, HistoneDemethylase, Histone Demethylase, RG 6016, RG6016, RG-6016

Field of Research

Epigenetics & Chromatin

Purity

99.40% (May vary between batches)

Solubility

H2O:56 mg/mL (184.65 mM) ; Ethanol:1 mg/mL (3.3 mM) ; DMSO:7.81 mg/mL (25.75 mM)

Smiles

Cl.Cl.NC1CCC (CC1) N[C@@H]1C[C@H]1c1ccccc1

Molecular Formula

C15H22N2·2HCl

Molecular Weight

303.27

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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