PD0166285
PD0166285 is a potent, nanomolar-range inhibitor of the Wee1 and Chk1 kinases, effectively abrogating the G2/M cell cycle checkpoint. This small molecule is utilized in cancer research to sensitize tumor cells to DNA-damaging agents in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
185039-89-8
Product Name Alternative
PD166285, PD-166285, PD 166285, PD 0166285, PD0166285, PD-0166285, inhibit, Myt1, Inhibitor, Apoptosis, Chk1, Wee1
Field of Research
Cell Biology
Purity
99.23% (May vary between batches)
Solubility
H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:93 mg/mL (181.49 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.44 mM) ; Ethanol:93 mg/mL (181.49 mM)
Smiles
CCN (CC) CCOc1ccc (Nc2ncc3cc (-c4c (Cl) cccc4Cl) c (=O) n (C) c3n2) cc1
Molecular Formula
C26H27Cl2N5O2
Molecular Weight
512.43
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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