PD0166285

PD0166285 is a potent, nanomolar-range inhibitor of the Wee1 and Chk1 kinases, effectively abrogating the G2/M cell cycle checkpoint. This small molecule is utilized in cancer research to sensitize tumor cells to DNA-damaging agents in both in vitro and in vivo experimental models.

Product Specifications

CAS Number

185039-89-8

Product Name Alternative

PD166285, PD-166285, PD 166285, PD 0166285, PD0166285, PD-0166285, inhibit, Myt1, Inhibitor, Apoptosis, Chk1, Wee1

Field of Research

Cell Biology

Purity

99.23% (May vary between batches)

Solubility

H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:93 mg/mL (181.49 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.44 mM) ; Ethanol:93 mg/mL (181.49 mM)