PHA-767491 hydrochloride
PHA-767491 hydrochloride is a potent and selective ATP-competitive dual inhibitor of Cdc7 and CDK9 kinases, with IC50 values of 10 nM and 34 nM, respectively. It exhibits significant selectivity over related kinases and has been utilized in vitro and in vivo to study cell cycle progression, transcription, and oncology research.
Product Specifications
CAS Number
942425-68-5
Product Name Alternative
Field of Research
Cell Biology, Metabolism Research, Signal Transduction, Stem Cell & Developmental Biology
Purity
98.00% (May vary between batches)
Solubility
DMSO:4.62 mg/mL (18.5 mM) ; H2O:25 mg/mL (100.12 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (4 mM)
Smiles
Cl.O=C1NCCc2[nH]c (cc12) -c1ccncc1
Molecular Formula
C12H12ClN3O
Molecular Weight
249.69
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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