Vps34-PIK-III
VPS34-IN2 (PIK-III) is a potent and selective VPS34 inhibitor that blocks autophagy, leading to the accumulation of autophagy substrates. It is a valuable chemical tool for studying autophagy mechanisms in both cellular and in vivo models across cancer and neurodegenerative disease research.
Product Specifications
CAS Number
1383716-40-2
Product Name Alternative
Autophagy, PI3K, PI3Kα, PI3Kδ, PI3Kγ, PI3Kβ, Vps34PIKIII, Vps-34-PIK-III, Vps34-PIK-III, Vps34 PIK III, Vps34
Field of Research
Cell Biology, Signal Transduction
Purity
98.21% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.26 mM) ; DMSO:60 mg/mL (187.88 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; Ethanol:59 mg/mL (184.74 mM)
Smiles
Nc1ncc (c (CC2CC2) n1) -c1ccnc (Nc2ccncc2) n1
Molecular Formula
C17H17N7
Molecular Weight
319.36
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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