Piperlongumine
Piperlongumine (Piplartine) is a bioactive alkaloid with demonstrated anti-tumor properties, primarily through the induction of reactive oxygen species (ROS) and apoptosis. It is widely used in cancer research, showing efficacy in both in vitro cell culture and in vivo xenograft models for studying oxidative stress-mediated cell death.
Product Specifications
CAS Number
20069-09-4
Product Name Alternative
Apoptosis, Autophagy, Bacterial, inhibit, Ferroptosis, ERK, Extracellular signal regulated kinases, Inhibitor, ROS, ReactiveOxygenSpecies, Reactive Oxygen Species, Piperlongumine, Piplartine, PPLGM
Field of Research
Cell Biology, Protein Biochemistry
Purity
>98%
Bioactivity
Glutathione sponge; Increases ROS
Form
Powder
Solubility
Soluble in DMSO (up to 25 mg/ml) .
Smiles
COc1cc (\C=C\C (=O) N2CCC=CC2=O) cc (OC) c1OC
Molecular Formula
C17H19NO5
Molecular Weight
317.34
Storage Conditions
RT
Notes
For research use only.
Other Product Names
(E) -1- (3- (3,4,5-trimethoxyphenyl) acryloyl) -5,6-dihydropyridin-2 (1H) -one
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