PX-478
PX-478 is a selective, orally active, and blood-brain barrier permeable HIF-1α inhibitor. It demonstrates antitumor activity in cancer research and has been shown in studies to protect pancreatic β-cell function, making it a compound of interest for type 2 diabetes research.
Product Specifications
CAS Number
685898-44-6
Product Name Alternative
Autophagy, HIFProlylHydroxylase, HIF ProlylHydroxylase, HIF Prolyl-Hydroxylase, HIF/HIF Prolyl-Hydroxylase, HIF/HIFProlylHydroxylase, HIF/HIF ProlylHydroxylase, HIF-1α, HIF, PX478, PX-478, PX 478
Field of Research
Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Metabolism Research
Purity
97.00% (May vary between batches)
Solubility
DMSO:50 mg/mL (126.86 mM) ; H2O:88.81 mM;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (12.69 mM)
Smiles
Cl.Cl.N[C@@H] (Cc1ccc (cc1) [N+] ([O-]) (CCCl) CCCl) C (O) =O
Molecular Formula
C13H20Cl4N2O3
Molecular Weight
394.12
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
RD-WNT5A-Ra-96Tests 96 Tests
Rat Wingless Type MMTV Integration Site Family, Member 5A (WNT5A) ELISA Kit
Sign In for Pricing
View Details 
