PX-478
PX-478 is a selective, orally active, and blood-brain barrier permeable HIF-1α inhibitor. It demonstrates antitumor activity in cancer research and has been shown in studies to protect pancreatic β-cell function, making it a compound of interest for type 2 diabetes research.
Product Specifications
CAS Number
685898-44-6
Product Name Alternative
Autophagy, HIFProlylHydroxylase, HIF ProlylHydroxylase, HIF Prolyl-Hydroxylase, HIF/HIF Prolyl-Hydroxylase, HIF/HIFProlylHydroxylase, HIF/HIF ProlylHydroxylase, HIF-1α, HIF, PX478, PX-478, PX 478
Field of Research
Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Metabolism Research
Purity
97.00% (May vary between batches)
Solubility
DMSO:50 mg/mL (126.86 mM) ; H2O:88.81 mM;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (12.69 mM)
Smiles
Cl.Cl.N[C@@H] (Cc1ccc (cc1) [N+] ([O-]) (CCCl) CCCl) C (O) =O
Molecular Formula
C13H20Cl4N2O3
Molecular Weight
394.12
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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