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Riociguat

Riociguat (BAY 632521) is a soluble guanylate cyclase (sGC) stimulator used in research for severe pulmonary arterial hypertension. It induces vasodilation by enhancing cGMP signaling and is applied in both in vitro mechanistic studies and in vivo animal models of pulmonary hypertension.

Product Specifications

CAS Number

625115-55-1

Product Name Alternative

BAY632521, BAY-632521, BAY 632521, guanylate cyclase, Guanylatecyclase, Guanylate Cyclase, Guanylate cyclase, Inhibitor, inhibit, Riociguat

Field of Research

Pharmacology & Drug Discovery

Purity

99.28% (May vary between batches)

Solubility

Ethanol:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.73 mM) ; DMSO:40.83 mg/mL (96.66 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble)

Smiles

COC (=O) N (C) c1c (N) nc (nc1N) -c1nn (Cc2ccccc2F) c2ncccc12

Molecular Formula

C20H19FN8O2

Molecular Weight

422.42

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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