What is the catalog number for Ro 5126766?

The catalog number for Ro 5126766 is orb1300300.

What sizes are available for Ro 5126766?

Ro 5126766 is available in the following size(s): 1 mg, 2 mg, 5 mg, 1 ml x 10 mM (in DMSO), 10 mg, 25 mg, 50 mg, 100 mg.

How many pack sizes does Ro 5126766 come in?

Ro 5126766 is available in 8 different pack sizes.

Is Ro 5126766 in stock?

Ro 5126766 is currently made to order / not held in immediate stock. Contact us for lead time.

Ro 5126766

RO5126766 (CH5126766) is a dual RAF/MEK inhibitor currently in Phase 1 clinical development. It potently inhibits BRAF V600E, BRAF, CRAF, and MEK1 with IC50 values ranging from 8.2 nM to 160 nM. This compound is a valuable research tool for investigating the MAPK pathway in both in vitro and in vivo cancer models.

Product Specifications

CAS Number

946128-88-7

Product Name Alternative

Inhibit, Mitogen-activated protein kinase kinase, MAP2K, MAPKK, MEK1, MEK, Inhibitor, C-Raf, CH5126766, CH-5126766, CH 5126766, Avutometinib, B-Raf (V600E), B-Raf, RO5126766, RO-5126766, Ro-5126766, Ro 5126766, Raf kinases, Raf, VS-6766

Field of Research

Signal Transduction

Purity

98.13% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween-80+45% Saline:5 mg/mL (10.61 mM) ; DMSO:87 mg/mL (184.53 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble)