Saccharin 1-methylimidazole
Saccharin 1-methylimidazole (SMI) is a versatile activating reagent employed in the chemical synthesis of oligonucleotides for both DNA and RNA. It facilitates phosphoramidite coupling in solid-phase synthesis, a foundational technique used extensively in vitro for constructing primers, probes, and synthetic genes in molecular biology and therapeutic research.
Product Specifications
CAS Number
482333-74-4
Product Name Alternative
DNA Synthesis, DNA/RNA Synthesis, DNASynthesis, Inhibitor, inhibit, Saccharin 1 methylimidazole, Saccharin 1methylimidazole, Saccharin 1-methylimidazole, Saccharin 1-methylimidazole (SMI), SMI, RNASynthesis, RNA Synthesis
Field of Research
Cell Biology, Molecular Biology
Purity
98.21% (May vary between batches)
Solubility
DMSO:6 mg/mL (22.62 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (3.77 mM)
Smiles
Cn1ccnc1.O=C1NS (=O) (=O) c2ccccc12
Molecular Formula
C7H5NO3S·C4H6N2
Molecular Weight
265.29
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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