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Saccharin 1-methylimidazole

Saccharin 1-methylimidazole (SMI) is a versatile activating reagent employed in the chemical synthesis of oligonucleotides for both DNA and RNA. It facilitates phosphoramidite coupling in solid-phase synthesis, a foundational technique used extensively in vitro for constructing primers, probes, and synthetic genes in molecular biology and therapeutic research.

Product Specifications

CAS Number

482333-74-4

Product Name Alternative

DNA Synthesis, DNA/RNA Synthesis, DNASynthesis, Inhibitor, inhibit, Saccharin 1 methylimidazole, Saccharin 1methylimidazole, Saccharin 1-methylimidazole, Saccharin 1-methylimidazole (SMI), SMI, RNASynthesis, RNA Synthesis

Field of Research

Cell Biology, Molecular Biology

Purity

98.21% (May vary between batches)

Solubility

DMSO:6 mg/mL (22.62 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (3.77 mM)

Smiles

Cn1ccnc1.O=C1NS (=O) (=O) c2ccccc12

Molecular Formula

C7H5NO3S·C4H6N2

Molecular Weight

265.29

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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