SB 239063
SB 239063 is a potent and selective inhibitor of p38 MAPK α and β isoforms, exhibiting an IC50 of 44 nM with no significant activity against the γ and δ isoforms. It is widely used in research to investigate inflammation, cellular stress responses, and cytokine signaling in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
193551-21-2
Product Name Alternative
Autophagy, Inhibitor, inhibit, p38 MAPK, p38MAPK, p38β, p38α, SB239063, SB-239063, SB 239063
Field of Research
Cell Biology, Signal Transduction
Purity
99.42% (May vary between batches)
Solubility
DMSO:3.7 mg/mL (10.04 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.71 mM)
Smiles
COc1nccc (n1) -c1c (ncn1[C@H]1CC[C@H] (O) CC1) -c1ccc (F) cc1
Molecular Formula
C20H21FN4O2
Molecular Weight
368.4
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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