Wilforine

Wilforine is a bioactive sesquiterpene pyridine alkaloid from Tripterygium wilfordii with demonstrated anti-fibrotic and anti-inflammatory properties, linked to the suppression of TNF-α, IL-6, and NO. Its bioactivity extends to insecticidal effects via Na+/K+-ATPase inhibition, supporting applications in pulmonary fibrosis research and neuropharmacological studies both in vitro and in vivo.

Product Specifications

CAS Number

11088-09-8

Product Name Alternative

Na+/K+-ATPase, inhibit, Inhibitor, Wilforine

Field of Research

Pharmacology & Drug Discovery

Purity

98.40% (May vary between batches)

Solubility

DMSO:50 mg/mL (57.61 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (2.3 mM)

Smiles

CC (OC[C@]12[C@@]34[C@@H] ([C@] ([C@H] ([C@H]2OC (C) =O) OC (C) =O) ([H]) [C@@] (O3) (COC (C5=CC=CN=C5CC[C@@H] (C (O[C@] ([C@@H] ([C@@H]1OC (C) =O) OC (C6=CC=CC=C6) =O) ([H]) [C@@]4 (O) C) =O) C) =O) C) OC (C) =O) =O