Ganoderic acid A
Ganoderic acid A is a bioactive triterpenoid that inhibits NF-κB and AP-1, demonstrating antitumor effects. It induces apoptosis and inhibits proliferation and invasion in osteosarcoma cells (HOS, MG-63) and enhances cisplatin sensitivity in HepG2 cells via STAT3 suppression. This compound is a valuable tool for cancer research in both in vitro and in vivo models.
Product Specifications
CAS Number
81907-62-2
Product Name Alternative
Endogenous Metabolite, Apoptosis, Autophagy, EndogenousMetabolite, Ganoderic acid A, NFkB, NFκB, NF-κB, NF-kB, Inhibitor, inhibit
Field of Research
Cell Biology, Metabolism Research, Signal Transduction
Purity
≥95% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:10 mg/mL (19.35 mM) ; DMSO:82.5 mg/mL (159.68 mM)
Smiles
C[C@H] (CC (=O) C[C@@H] (C) C (O) =O) [C@H]1C[C@H] (O) [C@@]2 (C) C3=C (C (=O) C[C@]12C) [C@@]1 (C) CCC (=O) C (C) (C) C1C[C@@H]3O
Molecular Formula
C30H44O7
Molecular Weight
516.67
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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