CM-272
CM-272 is a potent small molecule inhibitor targeting both G9a histone methyltransferase and DNA methyltransferases (DNMTs) . It is utilized in epigenetic research for studying cancer biology and has demonstrated activity in both cellular assays and in vivo animal models of hematological malignancies.
Product Specifications
CAS Number
1846570-31-7
Product Name Alternative
CM272, CM-272, CM 272, DNMTs, DNMT3B, DNMT3A, DNMT1, DNAMethyltransferase, DNA Methyltransferase, DNA MTases, DNA methyltransferase (DNMT), anti-tumour, Apoptosis, immunogenic, inhibit, epigenetics, G9a, GLP, H3K9me2, Inhibitor, HistoneMethyltransferase, Histone Methyltransferase, substrate-competitive
Field of Research
Cell Biology, Epigenetics & Chromatin
Purity
97.83% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.89 mM) ; DMSO:96 mg/mL (200.57 mM) ; Ethanol:96 mg/mL (200.57 mM)
Smiles
COc1cc2c (NC3CCN (C) CC3) cc (nc2cc1OCCCN1CCCC1) -c1ccc (C) o1
Molecular Formula
C28H38N4O3
Molecular Weight
478.63
Storage Conditions
-20°C
Notes
For research use only.
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