HG-10-102-01
HG-10-102-01 is a potent and selective small molecule inhibitor of LRRK2 kinase, demonstrating an IC50 of 20.3 nM. This compound is a valuable research tool for investigating LRRK2's role in Parkinson's disease pathogenesis, enabling both in vitro biochemical assays and in vivo disease model studies.
Product Specifications
CAS Number
1351758-81-0
Product Name Alternative
BBB, HEK293 cells, Inhibitor, HG1010201, HG-10-102-01, HG 10 102 01, MAPK interacting kinase, MAP kinase interacting kinase, Leucine-rich repeat kinase 2, Mouse embryonic fibroblast cells, Mouse Swiss 3T3 cells, inhibit, LRRK2, Parkinson's disease, Mitogen activated protein kinase interacting kinase, MNK, Radiosynthesis, Positron emission tomography, PET, Ser910, Ser935
Field of Research
Cell Biology, Signal Transduction
Purity
99.59% (May vary between batches)
Solubility
DMSO:50 mg/mL (132.33 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.29 mM)
Smiles
CNc1nc (Nc2ccc (cc2OC) C (=O) N2CCOCC2) ncc1Cl
Molecular Formula
C17H20ClN5O3
Molecular Weight
377.83
Storage Conditions
-20°C
Notes
For research use only.
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