E-4031 dihydrochloride
E-4031 dihydrochloride is a potent and selective class III antiarrhythmic agent that blocks the ERG potassium channel (IC50 = 29 nM), thereby prolonging the cardiac action potential. It is widely used in cardiovascular research to study long QT syndrome and arrhythmia mechanisms in both cellular electrophysiology and isolated tissue experiments.
Product Specifications
CAS Number
113559-13-0
Product Name Alternative
Potassium Channel, PotassiumChannel, hERG, hERG Potassium Channel, KcsA, inhibit, Inhibitor, E 4031, E4031, E-4031, anti-arrhythmic
Field of Research
Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction
Purity
97.71% (May vary between batches)
Solubility
H2O:135 mg/mL (284.55 mM)
Smiles
Cl.Cl.Cc1cccc (CCN2CCC (CC2) C (=O) c2ccc (NS (C) (=O) =O) cc2) n1
Molecular Formula
C21H29Cl2N3O3S
Molecular Weight
474.44
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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