TAK-960
TAK-960 is a potent, orally active small molecule inhibitor that selectively targets Polo-like kinases (Plks), demonstrating highest potency against Plk1 (IC50 = 0.8 nM) . It is a valuable research tool for investigating cell cycle progression and has shown antitumor activity in preclinical cancer models, supporting its use in both in vitro and in vivo studies.
Product Specifications
CAS Number
1137868-52-0
Product Name Alternative
Cancer, cell, Inhibitor, leukemia, lines, inhibit, PLK, mitosis, phosphorylation, Polo-like Kinase (PLK), TAK960, TAK-960, TAK 960, proliferation
Field of Research
Cell Biology, Epigenetics & Chromatin
Purity
97.06% (May vary between batches)
Solubility
DMSO:35 mg/mL (62.32 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (1.78 mM)
Smiles
COc1cc (C (=O) NC2CCN (C) CC2) c (F) cc1Nc1ncc2N (C) C (=O) C (F) (F) CN (C3CCCC3) c2n1
Molecular Formula
C27H34F3N7O3
Molecular Weight
561.6
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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