Nelociguat
Nelociguat (BAY60-4552) is a stimulator of soluble guanylate cyclase (sGC), a central enzyme in nitric oxide (NO) signaling. This research compound is used in vitro and in vivo to study cardiovascular and pulmonary diseases, including pulmonary hypertension, by potentiating the NO-sGC-cGMP pathway.
Product Specifications
CAS Number
625115-52-8
Product Name Alternative
Guanylate cyclase, Guanylatecyclase, Guanylate Cyclase, Inhibitor, inhibit, Nelociguat, BAY60-4552
Field of Research
Pharmacology & Drug Discovery
Purity
98.00% (May vary between batches)
Solubility
DMSO:4.09 mg/mL (10.01 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.45 mM)
Smiles
COC (=O) Nc1c (N) nc (nc1N) -c1nn (Cc2ccccc2F) c2ncccc12
Molecular Formula
C19H17FN8O2
Molecular Weight
408.39
Storage Conditions
-20°C
Notes
For research use only.
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