AMD 3465 hexahydrobromide
AMD 3465 hexahydrobromide, also known as GENZ-644494, is a selective CXCR4 chemokine receptor antagonist. It is utilized in oncology and virology research to investigate mechanisms of cancer metastasis and HIV-1 entry in vitro, with studies exploring its potential in preclinical models.
Product Specifications
CAS Number
185991-07-5
Product Name Alternative
CXCR, CXCL12AF647-CXCR4, CXC chemokine receptors, CXCR4, AMD 3465, AMD 3465 hexahydrobromide, AMD 3465 Hexahydrobromide, AMD3465, AMD-3465, AMD3465 Hexahydrobromide, AMD-3465 Hexahydrobromide, 12G5 mAb-CXCR4, inhibit, Inhibitor, GENZ 644494, GENZ-644494, GENZ-644494 (hexahydrobromide), GENZ-644494 hexahydrobromide, GENZ644494, Human immunodeficiency virus, HIV, HIV Protease, HIVProtease, HIV-2 (EHO), HIV-2 (ROD), X4 HIV-1 (HE), X4 HIV-1 (IIIB), X4 HIV-1 (NL4.3), X4 HIV-1 (NL4.3AMD3100), X4 HIV-1 (RF)
Field of Research
Cell Biology, Immunology & Inflammation, Infectious Disease & Virology, Pharmacology & Drug Discovery, Protein Biochemistry
Purity
99.03% (May vary between batches)
Solubility
DMSO:50 mg/mL (55.8 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (2.23 mM) ; H2O:38 mg/mL (42.41 mM)
Smiles
Br.Br.Br.Br.Br.Br.C (NCc1ccccn1) c1ccc (CN2CCCNCCNCCCNCC2) cc1
Molecular Formula
C24H44Br6N6
Molecular Weight
896.07
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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