Tenofovir alafenamide hemifumarate
Tenofovir alafenamide hemifumarate (GS-7340 hemifumarate) is a phosphonoamidate prodrug of tenofovir, designed for enhanced oral delivery and intracellular conversion to the active nucleotide analog against HIV reverse transcriptase. It is widely used in antiviral research for in vitro and in vivo studies of HIV-1 infection and treatment strategies.
Product Specifications
CAS Number
1392275-56-7
Product Name Alternative
Inhibit, Inhibitor, HIV, HIV-1, HIV Protease, HIVProtease, Human immunodeficiency virus, GS7340, GS-7340 hemifumarate, GS-7340, GS-7340 (hemifumarate), GS 7340, Tenofovir alafenamide, Tenofovir alafenamide Fumarate, Tenofovir alafenamide fumarate, Tenofovir alafenamide hemifumarate, Tenofovir alafenamide Hemifumarate, Reverse Transcriptase, ReverseTranscriptase
Field of Research
Infectious Disease & Virology, Pharmacology & Drug Discovery, Protein Biochemistry
Purity
98.37% (May vary between batches)
Solubility
DMSO:50 mg/mL (93.54 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.74 mM)
Smiles
OC (/C=C/C (O) =O) =O.CC (C) OC ([C@H] (C) NP (CO[C@H] (C) CN1C2=NC=NC (N) =C2N=C1) (OC3=CC=CC=C3) =O) =O.CC (C) OC ([C@H] (C) NP (CO[C@H] (C) CN4C5=NC=NC (N) =C5N=C4) (OC6=CC=CC=C6) =O) =O
Molecular Formula
C21H29N6O5P·1/2C4H4O4
Molecular Weight
534.51
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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