FITM
FITM is a highly potent and selective negative allosteric modulator of the metabotropic glutamate receptor 1 (mGlu1), exhibiting a Ki of 2.5 nM. This small molecule is a valuable research tool for investigating mGlu1 function in neurological disorders, with applications in both in vitro binding assays and in vivo pharmacological studies.
Product Specifications
CAS Number
932737-65-0
Product Name Alternative
FITM, Inhibitor, Metabotropic glutamate receptors, mGluR, mGluR1, inhibit
Field of Research
Neuroscience
Purity
≥95% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (10.77 mM) ; DMSO:150 mg/mL (403.84 mM)
Smiles
CC (C) Nc1cc (ncn1) -c1csc (n1) N (C) C (=O) c1ccc (F) cc1
Molecular Formula
C18H18FN5OS
Molecular Weight
371.43
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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