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FITM

FITM is a highly potent and selective negative allosteric modulator of the metabotropic glutamate receptor 1 (mGlu1), exhibiting a Ki of 2.5 nM. This small molecule is a valuable research tool for investigating mGlu1 function in neurological disorders, with applications in both in vitro binding assays and in vivo pharmacological studies.

Product Specifications

CAS Number

932737-65-0

Product Name Alternative

FITM, Inhibitor, Metabotropic glutamate receptors, mGluR, mGluR1, inhibit

Field of Research

Neuroscience

Purity

≥95% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (10.77 mM) ; DMSO:150 mg/mL (403.84 mM)

Smiles

CC (C) Nc1cc (ncn1) -c1csc (n1) N (C) C (=O) c1ccc (F) cc1

Molecular Formula

C18H18FN5OS

Molecular Weight

371.43

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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