JQEZ5
JQEZ5 is a potent and selective small molecule inhibitor of the EZH2 methyltransferase, with an IC50 of 11.1 nM. It is widely used in epigenetic research to study histone methylation's role in cancer biology, both in cellular assays and in vivo models.
Product Specifications
CAS Number
1913252-04-6
Product Name Alternative
Inhibit, JQEZ 5, JQEZ5, JQEZ-5, methionine, Inhibitor, Histone Methyltransferase, HistoneMethyltransferase, EZH2, H3K27me3, antitumor, PRC2, S-adenosyl
Field of Research
Epigenetics & Chromatin
Purity
≥98% (May vary between batches)
Solubility
DMSO:25 mg/mL (46.07 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.69 mM)
Smiles
CCCc1cc (C) [nH]c (=O) c1CNC (=O) c1cc (nc2n (ncc12) C (C) C) -c1ccc (nc1) N1CCN (C) CC1
Molecular Formula
C30H38N8O2
Molecular Weight
542.68
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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