BAY1125976
BAY1125976 is a potent and selective allosteric inhibitor of Akt1 and Akt2, with IC50 values of 5.2 nM and 18 nM, respectively. This compound is a valuable research tool for studying the PI3K/Akt pathway in cancer biology, supporting both in vitro cellular assays and in vivo preclinical models.
Product Specifications
CAS Number
1402608-02-9
Product Name Alternative
PKB, Protein kinase B, Akt, BAY1125976, BAY-1125976, BAY 1125976, Inhibitor, inhibit
Field of Research
Signal Transduction
Purity
≥98% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.61 mM) ; DMSO:5 mg/mL (13.04 mM)
Smiles
NC (=O) c1ccc2nc (c (-c3ccccc3) n2n1) -c1ccc (cc1) C1 (N) CCC1
Molecular Formula
C23H21N5O
Molecular Weight
383.45
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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