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BAY1125976

BAY1125976 is a potent and selective allosteric inhibitor of Akt1 and Akt2, with IC50 values of 5.2 nM and 18 nM, respectively. This compound is a valuable research tool for studying the PI3K/Akt pathway in cancer biology, supporting both in vitro cellular assays and in vivo preclinical models.

Product Specifications

CAS Number

1402608-02-9

Product Name Alternative

PKB, Protein kinase B, Akt, BAY1125976, BAY-1125976, BAY 1125976, Inhibitor, inhibit

Field of Research

Signal Transduction

Purity

≥98% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.61 mM) ; DMSO:5 mg/mL (13.04 mM)

Smiles

NC (=O) c1ccc2nc (c (-c3ccccc3) n2n1) -c1ccc (cc1) C1 (N) CCC1

Molecular Formula

C23H21N5O

Molecular Weight

383.45

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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