CU-CPT-9a

CU-CPT-9a is a highly potent and selective TLR8 inhibitor with an IC50 of 0.5 nM. It effectively blocks TLR8-driven inflammatory responses in diverse cellular models, including human primary cells. This tool compound is valuable for studying TLR8 biology in autoimmune, inflammatory, and infectious disease research contexts, both in vitro and in vivo.