CU-CPT-9a
CU-CPT-9a is a highly potent and selective TLR8 inhibitor with an IC50 of 0.5 nM. It effectively blocks TLR8-driven inflammatory responses in diverse cellular models, including human primary cells. This tool compound is valuable for studying TLR8 biology in autoimmune, inflammatory, and infectious disease research contexts, both in vitro and in vivo.
Product Specifications
CAS Number
2165340-32-7
Product Name Alternative
CU CPT 9a, CUCPT9a, CU-CPT-9a, inhibit, Inhibitor, Toll-like Receptor (TLR), TLR, TLR8
Field of Research
Immunology & Inflammation
Purity
98.00% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (15.08 mM) ; DMSO:150 mg/mL (565.38 mM)
Smiles
COc1ccc2c (ccnc2c1) -c1ccc (O) c (C) c1
Molecular Formula
C17H15NO2
Molecular Weight
265.31
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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