Pyrvinium pamoate
Pyrvinium pamoate is a classic anthelmintic agent for enterobiasis that has regained interest as a potential anticancer compound. It functions by inhibiting the Wnt/β-catenin signaling pathway, demonstrating activity in both in vitro cellular assays and in vivo animal models of colorectal and other cancers.
Product Specifications
CAS Number
3546-41-6
Product Name Alternative
Inhibit, Inhibitor, bcatenin, betacatenin, beta-catenin, Pyrvinium, Pyrvinium embonate, Pyrvinium pamoate, Wnt, Wnt/b-catenin, Wnt/betacatenin, Wnt/β-catenin, βcatenin
Field of Research
Pharmacology & Drug Discovery, Signal Transduction, Stem Cell & Developmental Biology
Purity
98.43% (May vary between batches)
Solubility
DMSO:9.62 mg/mL (16.71 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (1.74 mM)
Smiles
CN (C) c1ccc2[n+] (C) c (C=Cc3cc (C) n (c3C) -c3ccccc3) ccc2c1.CN (C) c1ccc2[n+] (C) c (C=Cc3cc (C) n (c3C) -c3ccccc3) ccc2c1.Oc1c (cc2ccccc2c1Cc1c (O) c (cc2ccccc12) C ([O-]) =O) C ([O-]) =O
Molecular Formula
C26H28N3 . 1/2 C23H14O6
Molecular Weight
575.71
Storage Conditions
-20°C
Notes
For research use only.
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