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Nelotanserin

Nelotanserin (APD125) is a potent and selective inverse agonist of the 5-HT2A receptor (IC50 = 1.7 nM), with moderate activity at 5-HT2C and weak activity at 5-HT2B. It is a valuable research tool for investigating serotonin receptor function in neuropharmacology, sleep disorders, and related in vitro and in vivo studies.

Product Specifications

CAS Number

839713-36-9

Product Name Alternative

5HTReceptor, 5HT Receptor, 5-HT, 5-hydroxytryptamine Receptor, 5-HT Receptor, APD125, APD-125, APD 125, Nelotanserin, inhibit, Inhibitor, Serotonin Receptor

Field of Research

Neuroscience, Pharmacology & Drug Discovery

Purity

98.01% (May vary between batches)

Solubility

DMSO:250 mg/mL (571.77 mM)

Smiles

COc1ccc (NC (=O) Nc2ccc (F) cc2F) cc1-c1c (Br) cnn1C

Molecular Formula

C18H15BrF2N4O2

Molecular Weight

437.24

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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