Acumapimod
Acumapimod (BCT-197) is an orally bioavailable small molecule that selectively inhibits p38α MAP kinase with an IC50 below 1 μM. It has been utilized in preclinical research to investigate p38α's role in inflammatory pathways, with studies demonstrating its activity in both cellular assays and animal models of inflammation.
Product Specifications
CAS Number
836683-15-9
Product Name Alternative
Acumapimod, BCT 197, BCT197, BCT-197, Autophagy, inhibit, Inhibitor, p38, p38 MAPK, p38MAPK
Field of Research
Cell Biology, Signal Transduction
Purity
≥95% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.19 mM) ; DMSO:50 mg/mL (129.73 mM)
Smiles
Cc1ccc (cc1-n1ncc (C (=O) c2cccc (c2) C#N) c1N) C (=O) NC1CC1
Molecular Formula
C22H19N5O2
Molecular Weight
385.42
Storage Conditions
-20°C
Notes
For research use only.
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