Talarozole
Talarozole (R115866) is an orally active RAMBA that potently inhibits CYP26A1 and CYP26B1, enzymes which catabolize retinoic acid. This inhibition elevates endogenous retinoid levels, underpinning its research use in models of acne, psoriasis, and related dermatological disorders.
Product Specifications
CAS Number
201410-53-9
Product Name Alternative
Autophagy, CYPs, CYP, Cytochrome P450, inhibit, Inhibitor, Talarozole, Retinoid Receptor, Retinoid X receptors, RetinoidReceptor, Retinoic acid receptors, R 115866, R115866, R-115866, RAMBA, RAR/RXR
Field of Research
Cell Biology, Metabolism Research
Purity
≥95% (May vary between batches)
Solubility
DMSO:36 mg/mL (95.36 mM) ;10% DMSO+90% Corn Oil:2 mg/mL (5.3 mM)
Smiles
CCC (CC) C (c1ccc (Nc2nc3ccccc3s2) cc1) n1cncn1
Molecular Formula
C21H23N5S
Molecular Weight
377.51
Storage Conditions
-20°C
Notes
For research use only.
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