Ocifisertib (CFI-400945 free base)
Ocifisertib (CFI-400945 free base) is an orally bioavailable, highly potent and selective PLK4 inhibitor with a Ki of 0.26 nM. This small molecule is a valuable research tool for studying centriole duplication and has demonstrated antitumor activity in both cellular assays and in vivo cancer models.
Product Specifications
CAS Number
1338806-73-7
Product Name Alternative
Ocifisertib, PLK4, CFI 400945, CFI 400945 free base, CFI400945, CFI-400945, CFI400945 free base, CFI-400945 free base
Field of Research
Cell Biology, Immunology & Inflammation
Purity
97.56% (May vary between batches)
Solubility
H2O:Insoluble; Ethanol:100 mg/mL (187.04 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (7.48 mM) ; DMSO:100 mg/mL (187.04 mM)
Smiles
O=C1[C@]2 ([C@@H] (C2) C=3C=C4C (=CC3) C (/C=C/C5=CC=C (CN6C[C@@H] (C) O[C@@H] (C) C6) C=C5) =NN4) C=7C (N1) =CC=C (OC) C7
Molecular Formula
C33H34N4O3
Molecular Weight
534.65
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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