WS-12
WS-12 is a high-potency, selective agonist of the TRPM8 ion channel, eliciting a robust cooling sensation with an EC50 of 193 nM. This small molecule is a valuable research tool for studying thermosensation, pain pathways, and channel pharmacology in both cellular and animal models.
Product Specifications
CAS Number
68489-09-8
Product Name Alternative
TRP Channel, TRPChannel, TRPM8, TRPV Channel, TRPVChannel, Transient receptor potential channels, WS12, WS-12, WS 12, HEK293T, Inhibitor, inhibit, cultured mouse DRG neurons, chronic neuropathic pain, AVX 012, AVX012, AVX-012, AR15512, AR-15512, AR 15512, analgesic effect
Field of Research
Pharmacology & Drug Discovery
Purity
99.71% (May vary between batches)
Solubility
DMSO:50 mg/mL (172.77 mM) ;10% DMSO+90% Corn Oil:2.5 mg/mL (8.64 mM)
Smiles
C (NC1=CC=C (OC) C=C1) (=O) [C@H]2[C@H] ([C@H] (C) C) CC[C@@H] (C) C2
Molecular Formula
C18H27NO2
Molecular Weight
289.41
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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