Diquafosol tetrasodium
Diquafosol Tetrasodium (INS365) is a selective P2Y2 receptor agonist used in ophthalmic research. It promotes mucin and fluid secretion from ocular surface cells, enhancing tear film stability in models of dry eye disease. This mechanism supports its investigation in both in vitro cellular assays and in vivo animal studies.
Product Specifications
CAS Number
211427-08-6
Product Name Alternative
Diquafosol, Diquafosol tetrasodium, inhibit, Inhibitor, INS 365, INS365, INS-365, P2Y, P2YReceptor, P2Y Receptor, P2Y2 receptor
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
98.25% (May vary between batches)
Solubility
DMSO:Insoluble; H2O:247.5 mg/mL (281.82 mM)
Smiles
O=c1ccn (C2OC (COP (=O) ([O-]) OP (=O) ([O-]) OP (=O) ([O-]) OP (=O) ([O-]) OCC3OC (n4ccc (=O) [nH]c4=O) C (O) C3O) C (O) C2O) c (=O) [nH]1.[Na+].[Na+].[Na+].[Na+]
Molecular Formula
C18H22N4Na4O23P4
Molecular Weight
878.23
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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