Cilofexor
Cilofexor is a potent and selective farnesoid X receptor (FXR) agonist. It functions by binding to and activating FXR, thereby inhibiting the interaction with synthetic peptide ligands. This small molecule is utilized in research on metabolic and liver diseases, including in vitro assays and in vivo models of cholestasis and NASH.
Product Specifications
CAS Number
1418274-28-8
Product Name Alternative
Antifibrotic, anti-inflammatory, Autophagy, Cilofexor, GS9674, GS-9674, GS 9674, FXR, inhibit, Inhibitor, NR1H4, nonsteroidal, oral, NASH, safety, PSC
Field of Research
Cell Biology, Metabolism Research
Purity
≥95% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (6.82 mM) ; DMSO:125 mg/mL (213 mM)
Smiles
OC (=O) c1ccnc (c1) N1CC (O) (C1) c1ccc (OCc2c (onc2-c2c (Cl) cccc2Cl) C2CC2) cc1Cl
Molecular Formula
C28H22Cl3N3O5
Molecular Weight
586.85
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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