2,4-Diamino-6-hydroxypyrimidine
2,4-Diamino-6-hydroxypyrimidine (DAHP) is a specific inhibitor of GTP cyclohydrolase I, the enzyme responsible for the rate-limiting step in de novo pterin biosynthesis. It is widely used in research to study tetrahydrobiopterin-dependent processes, nitric oxide synthase activity, and neurotransmitter synthesis in both cellular and animal models.
Product Specifications
CAS Number
56-06-4
Product Name Alternative
VCAM-1, ReactiveOxygenSpecies, Reactive Oxygen Species, GTP, GTP cyclohydrolase I, Inhibitor, NOS, NOSynthase, inhibit, NO Synthase, Nitric oxide synthases, NF-κB, 2,4 Diamino 6 hydroxypyrimidine, 2,4Diamino6hydroxypyrimidine, 2,4-Diamino-6-hydroxypyrimidine, BH4, DAHP, cyclohydrolase-I
Field of Research
Immunology & Inflammation, Metabolism Research, Signal Transduction
Purity
99.26% (May vary between batches)
Solubility
DMSO:60 mg/mL (475.74 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (7.93 mM)
Smiles
NC1=NC (N) =CC (=O) N1
Molecular Formula
C4H6N4O
Molecular Weight
126.12
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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