Verubecestat
Verubecestat (MK-8931) is a potent and selective BACE1 inhibitor. It has been widely used in preclinical in vitro and in vivo research to investigate Alzheimer's disease pathology by modulating amyloid-β peptide production.
Product Specifications
CAS Number
1286770-55-5
Product Name Alternative
Disease, Alzheimer's, Aβ40, b-Secretase, bSecretase, BetaSecretase, Beta-secretase, BACE, BACE1, BACE2, MK8931, MK-8931, MK 8931, orally, inhibit, Inhibitor, βSecretase, β-Secretase, Verubecestat
Field of Research
Neuroscience
Purity
92.24% (May vary between batches)
Solubility
Ethanol:5 mg/mL (12.21 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (8.06 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:81 mg/mL (197.85 mM)
Smiles
CN1C (N) =N[C@@] (C) (CS1 (=O) =O) c1cc (NC (=O) c2ccc (F) cn2) ccc1F
Molecular Formula
C17H17F2N5O3S
Molecular Weight
409.41
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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