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Vps34-IN-1

Vps34-IN-1 is a potent and selective inhibitor of Vps34, demonstrating an in vitro IC50 of 25 nM with minimal activity against class I and II PI3K isoforms. It is a valuable chemical tool for studying autophagy, endosomal trafficking, and related pathways in both cellular and in vivo research contexts.

Product Specifications

CAS Number

1383716-33-3

Product Name Alternative

Autophagy, inhibit, Inhibitor, PI3K, Phosphoinositide 3-kinase, Vps34, Vps34IN1, Vps-34-IN-1, VPS34-IN1, Vps34-IN-1, Vps34 IN 1

Field of Research

Cell Biology, Signal Transduction

Purity

95.16% (May vary between batches)

Solubility

Ethanol:79 mg/mL (185.49 mM) ; DMSO:79 mg/mL (185.49 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.7 mM)

Smiles

CC (C) (O) CNc1ncc (c (CC2CC2) n1) -c1ccnc (Nc2ccnc (Cl) c2) n1

Molecular Formula

C21H24ClN7O

Molecular Weight

425.91

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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