Vps34-IN-1
Vps34-IN-1 is a potent and selective inhibitor of Vps34, demonstrating an in vitro IC50 of 25 nM with minimal activity against class I and II PI3K isoforms. It is a valuable chemical tool for studying autophagy, endosomal trafficking, and related pathways in both cellular and in vivo research contexts.
Product Specifications
CAS Number
1383716-33-3
Product Name Alternative
Autophagy, inhibit, Inhibitor, PI3K, Phosphoinositide 3-kinase, Vps34, Vps34IN1, Vps-34-IN-1, VPS34-IN1, Vps34-IN-1, Vps34 IN 1
Field of Research
Cell Biology, Signal Transduction
Purity
95.16% (May vary between batches)
Solubility
Ethanol:79 mg/mL (185.49 mM) ; DMSO:79 mg/mL (185.49 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.7 mM)
Smiles
CC (C) (O) CNc1ncc (c (CC2CC2) n1) -c1ccnc (Nc2ccnc (Cl) c2) n1
Molecular Formula
C21H24ClN7O
Molecular Weight
425.91
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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