VR23
VR23 is a potent and selective proteasome inhibitor, exhibiting nanomolar IC50 values against trypsin-like (1 nM) and chymotrypsin-like (50-100 nM) activities. Its distinct inhibitory profile makes it a valuable research tool for studying proteasome function in cellular and biochemical assays, including investigations into protein degradation pathways and related disease models.
Product Specifications
CAS Number
1624602-30-7
Product Name Alternative
Inhibit, Inhibitor, Chymotrypsin-like proteasomes, Caspase-like proteasomes, Apoptosis, Proteasome, Trypsin-like proteasomes, VR23, VR-23, VR 23
Field of Research
Cell Biology, Protein Biochemistry
Purity
98.99% (May vary between batches)
Solubility
DMSO:29 mg/mL (60.68 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; H2O:< 1 mg/mL (insoluble or slightly soluble)
Smiles
[O-][N+] (=O) c1ccc (c (c1) [N+] ([O-]) =O) S (=O) (=O) N1CCN (CC1) c1ccnc2cc (Cl) ccc12
Molecular Formula
C19H16ClN5O6S
Molecular Weight
477.88
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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