1,5-Isoquinolinediol
1,5-Isoquinolinediol is a potent PARP1 inhibitor (IC50: 0.39 μM) used to investigate DNA repair mechanisms and oxidant-induced apoptosis. This tool compound is applicable for both in vitro cellular studies and in vivo animal models of stress and disease.
Product Specifications
CAS Number
5154-02-9
Product Name Alternative
Diabetic, 1,5 Isoquinolinediol, 1,5Isoquinolinediol, 1,5-Isoquinolinediol, 1188540, inhibit, PARP, PARP1, NADPH, Inhibitor, retinopathy, stress, poly ADP ribose polymerase, oxidase, oxidative
Field of Research
Epigenetics & Chromatin, Molecular Biology
Purity
98.29% (May vary between batches)
Solubility
Ethanol:20 mg/mL (124.1 mM) ; H2O:1 mg/mL (6.21 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (12.41 mM) ; DMSO:55 mg/mL (341.28 mM)
Smiles
Oc1cccc2c (O) nccc12
Molecular Formula
C9H7NO2
Molecular Weight
161.16
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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